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KMID : 0897520100150020067
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Journal of Korean Association of Social Psychiatry
2010 Volume.15 No. 2 p.67 ~ p.73
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Attitudes of Patients with Schizophrenia and Their Caretakers Toward Treatment with Long-acting Injectable Antipsychotic Medication
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Kang Gwon-Young
Kang Shi-Hyun
Yoon Hae-Joo
Lee Jong-Il
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Abstract
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Objects：The poor compliance of patients with schizophrenia is the major cause of recurrence and lead to the poor prognosis. Long-acting injectable antipsychotic agent may be a benefit to lower the risk of relapse to elevate drug compliance. The general attitudes toward LAI(Long-acting Injection) have never been investigated in schizophrenics. Thus this study examined the general awareness and the perspective on LAI in patients with schizophrenia and their care-givers.
MethodsWe surveyed 1004 schizophrenic patients and 253 caregivers who visited the Seoul National Hospital on the attitudes toward LAI by questionnaires which include the type of antipsychotic medication and reasons to prefer. The study was conducted from November 2008 to May 2009.
Results：Schizophrenic patients(22.5%) knew about LAI more than care-givers(14.1%). 27.6% of patients and 27.5% of care-givers preferred on LAI, but 54.6% and 50.4% preferred on oral agents respectively. Comparing according to demographic and clinical characteristic factors, female schizophrenic patients showed the more preference on LAI than male patients(p<0.05). Less intervals of out-patient visit and more educational level, subjects have a higher preference on LAI. Subjects reported the reasons about preference on LAI that are good efficacy, safety, and faster curing of symptoms, improvement of the compliance, and not to take daily. They reported the reasons about hatred that LAI is to be expensive and more toxic, to have more side effects, to be used on last stage of treatment , to make the phobia to needle and pain during injection and to need the frequent visiting.
Conclusions：More subjects(27.6%) showed the preference on LAI in comparison of low real prescription rate(0.7%). But many subjects showed erroneous perception on LAI and need to educate about information of agent in schizophrenic patients and their care-givers.
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KEYWORD
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Long-acting injectable antipsychotic medication, Schizophrenia, Attitudes
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